Hi I’m a newbie and have some questions.
The creations I have seen with this program are fantastic, but do you earn a living with it? meaning, this can’t be just a hobby looking at for example pixolators creations.
Are those sold or used in games/movies?
In other words, what are those creations used for in general.
I can’t answer the question specifically (i.e. what such-and-such a creature was for), but I think I can give you some ideas as to how to use ZBrush commercially.
ZBrush can be used as a 3D modeling tool
In this way you can use ZBrush to create very detailed 3D models for a wide variety of uses, whether for a final, still render or for animation. Just think of 3D and you get the picture.
ZBrush can be used for low-poly modeling
Though this is not ZBrush’s strongest area, you can indeed use ZBrush to model low-poly models for games and other real-time 3D applications. With the recent release of Z2 it is even better because you can create, at the same time, a low-poly and hi-resolution model of the same thing. Thus you can use one for animations and cut scenes while the low-poly model is used in game.
ZBrush is a 3D painting tool
With this in mind you can import 3D models (or create them in ZBrush) and paint the skins on them in a very unique way.
ZBrush is a 2D painting tool
You can paint in ZBrush like you would in Photoshop, Painter, etc. So you can use ZBrush for all sorts of 2D illustrations.
ZBrush is all of this at the same time … and more!
This means that you can do all of the above (and more) all at the same time. Model, paint (2D and “2.5D”) and create a final composition for your client.
How do you make money with ZBrush? That is up to you, your imagination and your work flow. For some it is a tool to add details to an existing model more quickly then you could in a traditional modeler. This saves time and, as you know, time is money. For others it is a unique way to create unique illustrations for their clients. The uses for ZBrush are as varied as the medium it covers.
It’s also one helluvalot of fun!
Zbrush is a fantastic “toy” (in the meaning of tool) for all the digital images ! 2D, 2.5D and yes 3D 
Pilou
ps He can quasi all make!
pss For sculpting and modeling organic form, you can’t find better !
Psss For the real time, you can’t find better !
Pssss you will find it in all graphic pipeline in soon time !
Psssss If you are a graphist learn it, it will be soon a new standard
Antaris I use ZBrush almost exclusively for my freelance work. Most of my work is for still panel images or graphics to be used on display material. ZBrush allows me the benefits of using editable 3d images but in a very fast production manner.
Having heard from a few of the professionals…
I would guess that the majority of the images posted here are not by ‘professionals’ who earn a living at what they do. To me there is no difference in the quality of the art produced by someone who’s paid & someone who’s not. The only difference it the talent of the artist. (you can have crap art by a pro and stunning art by an amateur).
This is a debate I’ve seen many times in music production forums. ie. “if you’re not getting paid for it, it can’t be any good”. I think this is something the music industry indirectly tries to encourage as a way of bolstering their fight against filesharing.
What they don’t seem to understand (or won’t admit) is that even if people aren’t paid to make art (pictures, music, whatever) people will do it anyway!
It’s just too much fun for humans not too 
Sorry if I’ve waffled on a bit, but the first post just set me thinking
I guess what I’m saying is that most people do art for arts sake.
Sleeper
“All art is quite useless.” – Oscar Wilde 
Indeed
Check my location in my profile
Making money with Zbrush.
Like the gold rush the money was made selling supplies, so pixolater is in the best position to make money on Zbrush.
The first using it have a greater chance of making a ‘name’ and using that name to get them work or other opportunities.
In the end Zbrush will be used in conjunction will other artist tools and those unique results will help some to get work illustrating etc.
A few will use Zbrush to drive an entirely different business as happens with other 3D software.
Examples would be the jewelry business, or car design etc, or charcter design for movies etc.
Its true though, that if you made the drawing of creatures, robots, cyborgs, space ships and women with large breasts illegal, the entire 3D industry would collapse.
The tools don’t make people creative, and like in the gold rush only a few actually found the gold.
I think what needs to be pointed out here is that ZBrush is just a tool. Nothing more. Nothing less. It is a cool tool (to be sure) but it is a tool. How you make money with ZBrush depends on how you use the tool (or even if you have a use for the tool). So you need to ask yourself, do I need this tool? Will it fit into my pipeline and help me to create whatever it is I need to create?
I plan to use ZBrush for a variety of reasons after I get a bit better at actually using the product. The main area of use is to create skins for real-time 3D models. After that is 3D modeling and then illustration work. As time progresses and I get better at using ZBrush I may find it replaces other tools.
As was pointed out by the previous poster, the tools don’t make people creative. I create my own graphics. Not the tools. The tools are just a means to help me achieve an end. ZBrush is just another tool to help me get out what is already inside.
yes, yes/yes. In that order.