Not within Zbrush, that’s what the retopo tools are for. There are other tools (Such as topogun) which accomplish that task, and are a bit easier to use IMO.
The biggest problem I have with ZBs implementation is that the vertexes don’t snap to the surface when you split an edge. so, unless you plan ahead very well, you end up having to pull vertexes out from inside your reference mesh, which can be very difficult to do sometimes.
On the bright side, the topo doesn’t have to stick to the surface of the reference, so you can create details by moving the points after you’ve created them.
Also. It crashes alot.