(UPDATE - The issue has been mostly resolved (with much the thanks to Mr. Paul Gaboury) Its not an issue with Zbrush at all, It’s the current Wacom drivers for Mac. The Wacom drivers lag the entire system but its most noticeable so when the CPU is put under a heavy load, such as with Zbrush or Keyshot.
Use the the 6.3.37-2 drivers, any newer drivers up to 6.3.38-3 will slow your computer or stutter your mouse inputs. Wacom said they are now working on the problem but are not sure when a fix will be out.)
I am having performance issues with Zbrush 2020 on macOS 10.15.2. I think have narrowed it down to being a multithreading issue. If I have my MaxThreads count at 16 (the maximum for my system, 2019 3.6GHz 8-core iMac) Zbrush stutters and lags every few seconds. If I lower the MaxThreads it seems to alleviate the issue. As it is, I currently get better performance using 1 thread rather than 16. Also. I am not sure if it is related but I noticed that just moving the cursor within Zbrush, without doing anything else, maxes out my processing power which is less than ideal…
Here is a video demonstrating the issues.
I have submitted a support ticket for this issues but have yet to get back a response. If you are a Mac user and experiencing the same problem, try lowering the MaxThreads and hopefully it will help with the issue until it can be fixed proper.