Ortho’s work great for front/side/top etc… view, because you’re not worrying about perspective in those views.
However, as soon as you start getting into 3/4 views, you loose all sense of appropriate proportion due to the orthographic view completely killing any “natural” perspective we see in a 3/4 view. It’s hard to judge proportions and how they relate to each other in an orthographic 3/4 view.
That’s probably my biggest pet peeve of Zbrush as of right now. The Mac version has perspective sculpting, although not exactly what I was expecting, but hopefully Pixologic will give us the option to adjust the perspective view in 2.5 like you would in other 3D apps.
Ofer’s tip is something I’ve been doing for awhile. Although I use Silo to crease edges so it works a bit different than what other apps might do, i.e. it creates extra edges to simulate creasing. So I generally can’t reconstruct all the way to the base cage because of the extra edges it adds. What app are you using to crease your edges in Bay? Mirai?