I saved out a work in progress mesh last night that I’m re-topologizing with the wireframe attached. I open the file today, when I try to make edits to the wire frame doesn’t update. Though, it will update in the adaptive skin menu. My model is about 2mil polys. Not sure whats going on.
I think according to Aurick you have to turn the edit topology button off and back on unless I’m wrong, try it
Woah thanks dude!..that worked! 
I was trying to figure out for like 2 hours >_>…
Cool!