OK I’m not sure if I’m doing something wrong or I have a setting incorrect somewhere. Or I’m just assuming/hoping that transpose is useful for making major model movements… but so far not been having much luck.
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looks like something that happened to me after i had scaled up a tool to fit in with another mesh
so either your mesh is too big and needs to be uniformly scaled down or the transpose tools are of a finite inluence- either way the solution is probably to make everything smaller
Even with an all Zbrush mesh straight from zspheres?
I was unaware you could make a model in zbrush thats too big for zbrush to handle correctly? o.O
actually it takes a a few try’s to ge the tranpose thing down…i like you had to learn by doing and for me i have found rigging works better for big moves and for finessing transpose is better…
one of the things i learned tho is that transpose works better with higher res meshes…for me anyways…cus then the masking can do more in the fade/blur…which allows a tad more give when it comes to joints etc…i don’t think it was really designed for huge moves tho…thats what the rigging is for…but
i am a z3 newb too…so take my opinion for what it is…
well a Z3 noob and a fellow chicagoian 
I was hoping transpose would be useful for making a pose… not just tweaking a pre rigged mesh… though thats how its appearing so far… no big movements…
well ya can’t be all bad then eh? 
just kidding
what i was try to convey i guess is that the transpose works really well but for me at least with higher res’s cus that allows the masking a greater amount of flexability in the blur and movement.
i really recommend grabbing some crappy uv’d old mesh ya might have laying around…a quadraped…and load that in zb and playing with transpose…get the hang of the masking…get the hang of moving…watch…now load something you know is uv’s to move well…do the same…with your newly learned skills…you will see it does work…and you will see when it doesn’t…and why rigging vs transpose and vice versa are sometimes necessary.
you weren’t wrong in your thought…just need to understand how they work a bit better…took me a read or two as well…i am rather impatient and like to hop in…but zb taught me…it ain’t like what i know…it’s more intuitive…for me at least…but i do be abby normal. …
oh yeah
you’ll need your umbrella tomorrow or monday…i think knee is leaning towards monday 
You’re obviously using MOVE instead of rotate to try and position the arms. Switch to rotate first, I think this will work much better.
runs headlong into a big tree
Well heres the damn forest…
I swear I wanna jump out the window for totally blanking on that… I got the word move into my head and totally blanked on rotate…
feels like a moron now 