I’m having a lot of freezing and crashing issues on my Mac as well. I never had issues like this with 3.2 (or 3.12 for that matter) and I don’t know if I need to tweak some settings or what. I don’t have a super powerful machine, but past versions of ZBrush have always been pretty darn stable for me in the past. My system specs are very similar to yours mykyl.
EDIT
I found this on the Support Forum, but I didn’t have that “Universal Access” box checked so it doesn’t really help me, but maybe it’ll work for you. Here’s the info:
If you are experiencing excessive crashing with ZBrush 4 on OS X, try the following:
Go to your Mac’s Universal Access settings and disable the “enable access for assistive devices” setting.
Users who have been experiencing a lot of crashes have reported that doing this resolved their issues completely.
In any case it is also good to check your settings in the Preferences>Mem menu within ZBrush:
Compact Mem should be set to be 1000 lower than your total system memory, up to a maximum of 4096. If you have a 32-bit OS you should set this value no higher than 2048.
Undo settings should be left at the default of 4. You can temporarily raise these higher if a specific situation calls for it, but keeping them permanently higher robs ZBrush of resources and invites crashes.
Max Polys per Mesh should be no higher than twice the default value that ZBrush selects based upon your system resources.
HD Preview’s value should be reduced to increase performance rather than increased. This only has any effect when working with HD levels, however.