Im looking for the hotkey that saves your current layout, brushes, canvas setting, menus, etc as the defult layout when you startup Zbrush. I cannot for the life of me remember this hotkey! I have tried a blank canvas and hitting Save As and labeling it startupdocument.zbr in the ZStartup folder but that doesnt work.
…Cant believe I couldnt find it hahaha…
If anyone knows, itd be greatly appreciated!
Ctrl+Shift+I

Hahaha, thanks aurick :o