Depends on how much further work you plan. The suggestions above can hide the issue, but as you can see the polygon flow got wrecked pretty bad and if you need to continue sculpting and experimenting with the object, it’s going to fight you. (I’ve done this same thing to myself on a model, so don’t feel bad.)
The long-term fix is is retopo and reproject onto a new symmetric mesh. In my case, I exported my level one to external modeller (Silo), fixed up the mesh the way I liked (and fixed some topo things that had been bothering me) and reimported as new tool. I then added the refined mesh as a subtool and worked through the Project All method.
Alternately, you can use ZB’s own retopo tools (there’s lots of threads/tuts on this) but I find them fussy, especially on extended structures like the horns unless I make sure my edge loops contain more than four points. (I like to use boxes to represent extended structures like limbs and horns, and ZB’s adaptive skin algolrithm tends to narf-up and get twisted to easiuly unless it has more geo to work with.)
HTH,
-K