YES! This is exactly the sort of thing I was hoping for. I quickly experimented just now and was able to get it to work when doing saturation and hue adjustments. I haven’t been able to get it to work with a texture that’s been “nudged” but I’ll experiment and see if its user error, or maybe I was at the wrong subdivision level, etc. There’s a better than average chance I’m overlooking something based on a previous lifetime’s experience 
Thanks so much for this info, I’d failed to find it anywhere in the manual or the tutorials or forums. But the tutorial descriptions had a tantalizing reference to the ability to do it. Plus the time spent learning workarounds was well-spent, still a newbie with Zbrush and there’s lots to learn.
EDIT:
I’ve been unable to get a texture back out with any nudge modifications intact, but other changes are being kept which already represents major progress.
I’m going to re-read the manual and watch the tutes on the nudge tool to see if I’ve overlooked anything. Specifically, I’m wondering if there is any way to “bake” the nudge mods to the texture in a manner similar to alt-turning the Restore dial? That’s actually what got me into this issue to start, was looking for a good workflow for using the nudge tool, then re-importing the nudged image to do further nudges. Nudge.
Thanks for the quick and useful help, though – even when I think I’ve got one tiny corner of the program figured out I realize there’s lots to learn. If the nudge mods should show up in the texture when it’s removed again from spotlight, I’d appreciate any guidance on what exactly needs to happen first. I feel I’ve tried all combinations I can think of and would at this point be satisfied even if the the answer “Can’t do that”.
I did discover that alt-turning the Restore dial when nothing but a nudge has been performed results in an Abnormal termination. Incidentally, this is a separate issue from the Abnormal Term arising when trying to use nudge without a tool loaded and on the canvas in Edit mode from the best I can observe.
Thanks, nudge.
Thudge.