HI
I Installed Zbrush just 2 days ago and Suddenly in the last hour after a day of playing with the software - when working in Spotlight - every time I press Z to enter paint mode Zbrush Crashes.
This worked nicely so far.
I tried other files and the crash occoured again.
SOLVED: Check my last reply
NIR
Mac or PC/OS?? What version(including patches)?
PC Win7 64 bit
ZB R6 - new install - purchased 2 days ago (!)
Interl I7 + 24 gigs RAM + nVidia GT470 card
did a reboot , re-Installed and what not and still getting it 
Should display ZB4R6 P2 if you’re up to date.
Yep - P2 alright
(Sorry for the delays since I live on the other side of the big blue - different GMT)
OK Guys
With the help of this link I managed to solve it (apparently)
(check the tips from the first reply)
https://www.youtube.com/watch?v=pbP3Ot_QS2E
Deleting the ZBrushData folder in the Users/Public/Public Documents and restarted Worked fine (tried once - hoping for the best)
NIR