I’ve just tried it. Crossover loads nicely and looks like a good app. However, ZBrush is not on their supported list, so has to be installed on a “you’re on your own…lotsa luck” basis. After two failed attempts I clicked on the link that takes you to the install log, which has many fails and “did not install” messages. Not being a code writer, this was Greek to me.
It just looks like, the way Crossover is designed, it has to be programmed to work with each individual app, one at a time. Obviously they haven’t gotten around to ZBrush yet. I sure hope they’re not doing it alphabetically! 
Maybe we should start a letter writing campaign?