ZBrushCentral

System Requirements questions

trying to get my head around a few things.
looking to build a new machine, as mine is struggling at this point.

zbrush is currently 64 bit. can it really handle all the memory i throw at it?
if not- will that be the case with zbrush 5 when it’s released?
i mean, if i put in something like 64 gb of ram into a machine, will it really be worth it?
similar question for the cpu cores. will zbrush make use of a 12 core setup, or is that overkill?
one last one- will pci based flash storage for the scratch disk be worth the expense vs an ssd on sata 2 or 3, when it come to performance with zbrush?

any insights are solid gold. i really appreciate any help!