ZBrushCentral

Sculpting a high poly displacement map

Hello guys,
I am wondering at the moment how to best approach sculpting on ‘displaced’, high polygon objects and would like to hear some opinions about previous experience or gained knowledge.
Basically I have an object with a 4k displacement texture, generated with Octane in C4D. Now I use ZBrush to import the geometry ideally without any quality loss and start deforming, which ends up to be challenging: do I apply the .exr displacement map inside ZBrush and use this geometry for sculpting, or would it be better to bake displacement, normal and AO map in C4D on my object and then import? Would extreme defomation affect my in C4D generated displacement map in a negative way?
Is the baking process in C4D necessary at all? I do need a high quality object to sculpt with, it is just a matter of finding the right way.
I would be thankful to hear any comments and ideas!
Thanks in advance!