I’ll also mention that in the menu’s to the right there is a section display properties , if you want to look at your model smoothed out : slide smooth from 0 to 1 and then go into the transform menu and disable the option “quick edit” , you will need to re-enable it to be able to sculpt again.
About the 2d , its probably out of edit mode and dropped to the canvas , do layer -> clear and look in your tool palette, if you saved it as a file (not document), your tool should be in the list to redraw on the canvas and re-enter edit mode. If you did save it as a document , i’m afraid you lost your work. To save your model , either use Tool->save or File->save. Tool will only contain the tool , File will load zbrush the way it was when you saved it, with all the tools in the tool palette you made that session , materials , render settings , lighting settings.
Based on your questions you should really spend a day or 2 watching as many videos as you can though. Zclassroom.
http://www.d3d.it/resources/zbrushr2/
http://zbrush.info
http://www.pixologic.com/zclassroom/
http://www.youtube.com/user/rkingslien
commercial dvd tutorials will most likely explain you a complete project from scratch. But some of the free videos out there are very informative too.
The problem with Zbrush’s manual/tutorials/videos/information on the net is the negative side-effect of something very positive. Zbrush versions are not like traditional 3d packages that change small stuff and charge 1000$, the difference between zbrush versions is immense and therefor information on the net gets outdated fast.
One example is modeling, there only used to be the method to start from a sphere and if you wanted a complete body , you had to make every piece seperately and compose them as a scene on the document as 2.5d, Then Zspheres were introduced allowing you to build a skeleton fast and generate a complete basic model out of it, this changed Zbrush into a completely different program. Then they added subtools, zsketch to build mass and now the most common method of building a model is dynamesh.
With this I just want to show that they don’t add a function or 2 in upgrades, they change the entire method of sculpting because they found an easier/more intuitive way of doing things.