You could also try decimation master to lower the vert count of the sculpt prior to retopology as well. His suggestion to subdivide and project the mesh was aimed more at using qremesh, remesh, or a duplicated subtool with a lower dynamesh resolution. This way you would have an identical model to your current sculpt, but it would have several subdivision levels allowing you to step down to a less dense one.
Your comment is strange as well about Zbrush not being 64 bit, I know it isn’t but while I still had a 32 bit system pixologic was telling everyone that Zbrush would no longer be supported on 32 bit systems. What’s up with that? I upgrade to a new PC and now someones
telling me 64 bit isn’t supported or doesn’t make a difference? No offense.
Do you have a copy of this message, such a thing would be news to me. The only similar message I can recall is that they were dropping support of Windows XP, but that was due to the age of the OS and not due to the 32bit architecture.
Edit: I forgot to mention, but if quick saves are causing a problem for you then you can increase the time between saves in order to prevent it from interrupting you.