Zendo, if you have maya…as i do…do this:
Make the Uvs in maya in the o-1 space…then export .obj as usual. Go into Zbrush as usual and texture the object. When you export…only export the texture…its less clicking around and probably more efficient. The AutoUV tiles looks nice…but if you ever have to go into photoshop to hand paint something…its just not possible. If your Uvs are layed out in a way that makes visual sense, you can go in and paint the object. Thats my approach anyways because i have to be flexible enough to go between several apps for my job…and for somethings maya is faster…and for others pshop is faster…but zbrush is really fast and smooth(but crashes a lot!!) for painting models