What a great and fun thread, untimely revenant or not! 
Aurick, I hear you about the official wish-list forum, but I’m glad this unofficial thread exists:
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as a storage bin for good ideas that might otherwise be forgotten
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as a place where members can interact and mull over each other’s ideas, and pre-refine wishes before the djini comes out of the lamp 
But I do understand something along the lines of “okay, everyone out of the kitchen till I say so!” because that’s how I am
And I’m with Trent about wanting books, preferably several different ones, e.g. “Real World ZBrush” by Susan Kitchens or someone very much like her, “ZBrush Wow!”, “LOTZ”, “Star Wars Guys Show You How – With ZBrush”, “Master ZBrush Painting with Z. Beksinski”, etc.
So some musings:
As some heavy-duty users have mentioned, vector-based or font-based stenciling and masking would be nice – maybe also some kind of “auto feather and divide” function for the mesh to go with that
Maybe some integrated way to fetch and update the best utility zcripts (plugins) available, similar to the way JEdit handles plugin management
Analogous to virtual music-studio software, maybe a way to freeze/unfreeze objects – in some music software, which is generally more CPU- than RAM-intensive, individual midi tracks can be temporarily rendered into WAV files to reduce CPU usage (similar to ZBrush objects being converted into pixols) while preserving the original midi data plus effects settings for later editing – so perhaps optionally, each new 3d object would get its own layer and would turn into pixols as usual, but the tool would be more easily recallable for editing – it would of course mean more layers per document and more storage required, therefore optional
Or something like volumetric Z-grab – but that would mean that pixols representing the back surfaces would have to exist in the document – again, more storage
But maybe Pixolator or some topologist will have a revelation about how to represent meshes of any complexity in under 10 kb 